Sheldon Cheskes

- Associate Professor, Emergency Medicine, Family and Community Medicine, Faculty of Medicine, University of Toronto, Ontario, Canada

- Scientist, Keenan Research Institute, Li Ka Shing Knowledge Institute, St. Michael’s Hospital

- Medical Director, Regions of Halton and Peel, Sunnybrook Centre for Prehospital Medicine, Sunnybrook Health Sciences Centre

- Affiliate Scientist, Sunnybrook Research Institue 

- Co Principal Investigator, Toronto Regional Rescuenet, Resuscitation Outcomes Consortium, St. Michael’s Hospital

- Principal Investigator, Toronto Site, Canadian Resuscitation Outcomes Consortium (CanROC)

- Courtesy Staff, Department of Emergency Medicine, Sunnybrook Health Sciences Centre

- Active Staff, Department of Family Medicine, William Osler Health Centre, Brampton Civic Hospital

- Medical Director, Spectrum Patient Care Services, Ontario, Canada

- Medical Director, Mississauga Fire & Emergency Services

- Medical Director, Caledon Fire and Emergency Services

- Medical Director, Brampton Fire and Emergency Services

Research Synopsis

Dr. Cheskes research interests lay in the area of resuscitation science particularly the area of cardiac arrest resuscitation. He has a particular interest in CPR quality and its impact on cardiac arrest survival. He as well has interests in STEMI systems of care as well as pre-hospital airway management. Dr. Cheskes currently is a co principal investigator in studies exploring the impact of early prehospital treatment of sepsis (PITSTOP trial) as well as the impact of remote ischemic conditioning on clinical outcomes from STEMI (FIRST study). Finally innovative techniques in the treatment of refractory ventricular fibrillation (double sequential external defibrillaiton, ECMO) are an area of particular interest.

Recent Publications

Lane D, Wunsch H, Saskin R, Cheskes S, Lin S, Morrison L, Scales D. Assessing severity of illness in patients transported to hospital by paramedics: external validation of 3 prognostic scores. Prehospital Emergency Care 2019 https://doi.org/10.1080/10903127.2019.1632998. Co-Author.

Cheskes S. Double sequential external defibrillation for refractory ventricular fibrillation: It’s all about the timing. JEMS (in press). Principal Author.

Schmicker RH, Nichol G, Callaway CW, Cheskes S, Sopko G, Wang HE.Study Monitoring in Emergency Care Trials: Lessons from the Resuscitation Outcomes Consortium Continuous Chest Compressions Trial. Academic Emergency Medicine (in press). Co -Author

Cheskes S, Mcleod S, Wudwud A, Summers J, Turner L, Morrison LJ, Verbeek PR. The impact of double sequential external defibrillation on termination of refractory ventricular fibrillation during out-of-hospital cardiac arrest. Resuscitation 2019;139:275-281. Principal Author

Lane DJ , Blanchard IE, Cheskes S , Lazarenko G, Lin S, Morrison LJ, Saskin R, Seymour CW, Wunsch H, Scales DC. A strategy to identify paramedic transported sepsis cases in an Emergency Department administrative database. Prehospital Emergency Care, DOI: 10.1080/10903127.2019.1611978. Co-Author

Shuvy M, Koh M, Qiu F, Brooks SC, Chan TCY, Cheskes S, Dorian P, Geri G, Lin S, Scales DC, Ko DT.Health Care Utilization Prior to Out-of-hospital Cardiac Arrest: A Population-based Study. Resuscitation 2019 https://doi.org/10.1016/j.resuscitation.2019.04.033. Co-Author

Cheskes S, Vaillancourt C. Multiple Shocks or Early Transfer for Shock Refractory Ventricular Fibrillation. CJEM 2019;21(3):315–317. Invited editorial. Principal Author

Wong G, Welsford M, Ainsworth C, Abuzeid W, Fordyce CB, Greene J, Lambert L, Le May M, Lutchmedial S, Metha SR, Natarajan M, Norris CM, Overgaard C, Arnesen MP, Qurashi Au, Tanguay JF, Traboulsi M, Diepen SV, Welsh RC, Wood DA, Cantor WJ, Armstrong PW, Bagai A, Bainey K, Cairns J, Cheskes S, Ducas J, Dzavik V, Jolly S, Mcvey J, Schampaert E, Schnell G, So DY. 2019 Canadian Cardiovascular Society/Canadian Association of Interventional Cardiology Guidelines on the Acute Management of ST-Elevation Myocardial Infarction: Focused Update on Regionalization and Reperfusion. Canadian Journal of Cardiology 35 (2), 107-132. Co-Author

Cheskes S. High quality CPR requires Measure and Feedback. Invited commentary. JEMS Feb 15, 2019. https://www.jems.com/articles/supplements/special-topics/state-of-the-future-of-resuscitation/high-quality-cpr-requires-measurement-and-feedback.html Principal Author

Henry B, Verbeek PR, Cheskes S. Extracorporeal Cardiopulmonary Resuscitation in Out-of-Hospital Cardiac Arrest: Ethical Considerations. Resuscitation; (2019)137:1-6.Senior Responsible Author.

Allan KA, Morisson LJ, Pinter A, Tu J, Dorian P, Nascimiento B, Scales D, Ko D, Hutchison J, Dainty K, Swartz R, Verbeek PR, Rizoli S, Cheskes S, Brooks SC, Lin S, Chan T. Unexpected High Prevalence of Cardiovascular Disease Risk Factors and Psychiatric Disease Among Young People With Sudden Cardiac Arrest. JAHA January 2019. DOI: 10.1161/JAHA.118.010330 Co-Author.

Lane DJ, Wunsch H, Saskin R, Cheskes S, MD; Lin S, Morrison LJ, Scales DC. Association Between Early Intravenous Fluids Provided by Paramedics and Subsequent In-Hospital Mortality Among Patients With Sepsis. JAMA Network Open. 2018; 1(8):e185845. Co-Author.

Lipowicz AA, Cheskes S, Gray SH, Jeejeebhoy F, Lee J, Scales DC, Zhan C, Morrison LJ, On behalf of the Rescu Investigators. Incidence, Outcomes and Guideline Compliance of Out-of-Hospital Maternal Cardiac Arrest Resuscitations: A Population-based Cohort Study. Resuscitation:132 2018;137-132. Co-Author.

Okubo M, Schmicker RH, Wallace DJ, Idris AH, Nichol G, Austin MA, Grunau BE, Wittwer LK, Richmond N, Morrison LJ, Kurz MC, Cheskes S, Kudenchuk PJ, Zive DM, Aufderheide TP, Wang HE, Herren H, Vaillancourt C, Davis DP, Vilke GM, Scheuermeyer FX, Weisfeldt ML, Elmer J, Colella R, Callaway CW. for the Resuscitation Outcomes Consortium Investigators. Variation in Survival after Out-of-hospital Cardiac Arrest between Emergency-Medical-Services Agencies. JAMA Cardiol. 2018; 3(10):989-999. Co-Author.

Salcido DD, Schmicker RH, Kime N, Buick JE, Cheskes S, Grunau B, Zellner S, Zive D, Aufderheide TP, Koller AC, Herren H, Nuttall J, Sundermann ML, Menegazzi JJ, for The Resuscitation Outcomes Consortium Investigators. Effects of Intra-Resuscitation Antiarrhythmic Administration on Rearrest Occurrence and Intra-Resuscitation ECG Characteristics in the ROC ALPS Trial. Resuscitation 2018;129:6-12. Co-Author.

Kurz MC ,Schmicker RH, Leroux B, Nichol G, Aufderheide TP, Cheskes S, Gray R, Grunau B, Jasti J, Kudenchuk P, Vilke G, Buick J, Wittmer L, Sahni R, Brienza A, Straight R, Wang HE for the ROC Investigators. Advanced vs. Basic Life Support in the Treatment of Out-of-Hospital Cardiopulmonary Arrest in the Resuscitation Outcomes Consortium. Resuscitation April 2018;128:132-137. Co-Author.

Hansen ML, Schmicker RH, Newgard C, Rea TD, Egan D, Herren H, Grunau B, Scheuermeyer F, Cheskes S, Hutchison J, Alnaji F, Austin M, Colella R, Idris A, Vithalani V, Daya M. Time to Epinephrine Administration and Survival from Out-of-Hospital Cardiac Arrest presenting with Non-Shockable Rhythms.Circulation 10.1161/CIRCULATIONAHA.117.033067.Co-Author.

Buick J, Drennan I, Cheskes S, Brooks S, Byers A, Feldman M, Verbeek R, Morrison J, Zahn C, Scales D, Lin S, Improving Temporal Trends in Survival and Neurological Outcomes after Out-of-Hospital Cardiac Arrest. Circ Cardiovasc Qual Outcomes. 2018;11:e003561. DOI: 10.1161/CIRCOUTCOMES.117.003561 Co-Author.

Kwong, J., Ross, G., Turner, L., Olynyk, C., Cheskes, S., Thurston, A., & Verbeek, P. (2017). Evaluation of a primary care paramedic STEMI bypass guideline. November 2017 CJEM, 1-7. doi:10.1017/cem.2017.415 Co-Author.

Cheskes S. High School CPR: Is only an app away!! Invited Editorial. Resuscitation 2017 120:A9-A10. Principal Author.

Mcleod SM, Brignardello-Petersen R, Worster A,You J, Iansavichene A, Guyatt G, Cheskes S. Comparative Effectiveness of Antiarrhythmics for Out-of-Hospital Cardiac Arrest: A Systematic Review and Network Meta-Analysis. Resuscitation, December 2017;121:90-97.Senior Responsible Author.

Scales DC, Cheskes S, Verbeek RP, Pinto R, Austin D, Brooks SC, Dainty KN, Goncharenko K, Mamdani M, Thorpe KE, and Morrison LJ on behalf of the Strategies for Post-Arrest Care (SPARC) Network. Prehospital Cooling to Improve Targeted Temperature Management After Cardiac Arrest: A Randomized Controlled Trial. Resuscitation December 2017;121:187-194. Co-Author.

Landry CH, Allan KS, Connelly KA, Cunningham K, Morrison LJ, Dorian P; Rescu Investigators. Sudden Cardiac Arrest during Participation in Competitive Sports N Engl J Med. 2017 Nov 16;377(20):1943-1953. Co-Author.

Ho, E, Cheskes S, Angaran P, MD, Morrison LJ, MD, Aves T, Zhan C, Ko D, MD, Dorian P, MD on behalf of the Rescu Epistry Investigators. Implantable Cardioverter Defibrillator Implantation Rates After Out of Hospital Cardiac Arrest: Are the Rates Guideline-Concordant? Canadian Journal of Cardiology 2017;33:1266–1273.Co-Author.

Lee M, Demirtaş D, Buick JE, Ng A, Feldman MJ, Cheskes S, Morrison LJ, Chan TCY on behalf of the Rescu Epistry Investigators. Increased Cardiac Arrest Survival and Bystander Intervention in Enclosed Pedestrian Walkway Systems. Resuscitation 2017;118:1-7.Co-Author.

Brooks SC, Schmicker RH, Cheskes S, Christenson J, Craig AM, Daya M, Kudenchuk PJ, Nichol G, Zive D, Morrison LJM on behalf of the Resuscitation Outcomes Consortium Investigators. Variability in the initiation of resuscitation attempts by emergency medical services personnel during out-of-hospital cardiac arrest. Resuscitation 2017;117:102-108. Co-Author.

Cheskes S, Schmicker R, Morrison LJ, Rea T, Grunau B, Drennan IR, Leroux B, Vaillancourt C, Schmidt T, Koller A, Kudenchuk P, Aufderheide TP, Herren H, Vilke G, Flickinger K, Charleston M, Straight R, Christenson J on behalf of the Resuscitation Outcomes Consortium. The Association between AHA CPR Quality Guideline Compliance and Clinical Outcomes from Out-of-Hospital Cardiac Arrest. Resuscitation 2017;116:39-45.Principal Author.

Salcido DD, Schmicker RH, Buick JE, Cheskes S, Grunau B, Kudenchuk P, Leroux B, Zellner S, Zive D, Aufderheide TP, Koller AC, Herren H, Nuttall J, Sundermann ML, Menegazzi JJ for the Resuscitation Outcomes Consortium Investigators. Compression-to-Ventilation Ratio and Incidence of Rearrest: A Secondary Analysis of the ROC CCC Trial. Resuscitation 2017;115:68-74.Co-author.

Mcleod SM, Iansavichene E, Cheskes S. Remote ischemic per-conditioning to reduce reperfusion injury during acute STEMI: A systematic review and meta-analy. Journal of the American Heart Association https://doi.org/10.1161/JAHA.117.005522 Senior Responsible Author.

Cheskes S, Byers A, Zhan C, Verbeek PR, Ko D, Drennan IR, Buick JE, Brooks SC, Lin S, Taher A, Morrison LJ. Reply to: Performing cardiopulmonary resuscitation during ambulance transport: Safety and efficacy. Resuscitation. 2017 Jul;116:e17.doi: 10.1016/j.resuscitation.2017.04.034. Epub 2017 May 2. . Prinicipal Author.

Cheskes S, Zhan C, Drennan I, Brooks S, Byers A, Ko D, Verbeek R, Lin S, Buick J,Taher A, Morrison L on behalf of the Rescu Investigators. Cpr Quality During Out- Of- Hospital Cardiac Arrest Transport. Resuscitation. 2017;114:34-39. Principal Author.

Boutilier JJ, Brooks SC, Janmohamed A, Byers A, Zhan C, Buick JE, Schoellig AP, Morrison LJ, Cheskes S, Timothy Chan on behalf of the Rescu Investigators. Quantifying the Value of Drone-Delivered Automated External Defibrillators in Cardiac Arrest Response. Circulation 2017;135:2454-2465.Co-author.

Morrison LJ, Devlin SM, Kontos MC, Cheskes S, Aufderheide TP, Christenson J, Ornato JP, Stiell IG, Rac VE, Thomas AJ, Wigginton JG, Dorian P on behalf of the Resuscitation Outcomes Consortium Investigators. The association of maximum Troponin values post out-of-hospital cardiac arrest with electrocardiographic findings, cardiac reperfusion procedures and survival to discharge; A Sub-study of ROC PRIMED. Resuscitation.2017;111:82-89. Co-author.

Pound J, Verbeek R, Cheskes S. CPR induced consciousness during out-of-hospital cardiac arrest: A case report on an emerging phenomenon. Prehospital Emergency Care. 2016 Aug 23. http://dx.doi.org/10.1080/10903127.2016.1229823 Senior Responsible Author.

Ko DT, Qiu F, Koh M, Dorian P, Cheskes S, Austin P, Scales DC, Wijeysundera HC, Verbeek PR, Drennan I, Ng T, Tu JV, Morrison LJ. Factors associated with out-of-hospital cardiac arrest with pulseless electric activity: A population based study. American Heart Journal. 2016;177:129-137. Co-author.

Kudenchuk PJ, Brown SP, Daya M, Rea T, Nichol G, Morrison LJ, Leroux B, Vaillancourt C, Wittwer L, Callaway CW, Christenson J, Egan D, Ornato JP, Weisfeldt ML, Stiell IG, Idris AH, Aufderheide TP, Dunford JV, Colella MR, Vilke GM, Brienza AM, Desvigne‑Nickens P, Gray PC,Gray R, Seals N, Straight R, and Dorian P, for the Resuscitation Outcomes Consortium Investigators*. Amiodarone, Lidocaine, or Placebo in Out-of-Hospital Cardiac Arrest. New England Journal of Medicine. 2016;374:1711-1722. Co-author.

Grunau B; Reynolds, J; Scheuermeyer, F; Stenstrom, R; Stub D; Pennington, S; Cheskes, S; Ramanathan, K; Christenson, J. The relationship between time-to-ROSC and survival in outof-hospital cardiac arrest ECPR candidates: When is the best time to consider transport to hospital? Prehospital Emergency Care. 2016 Mar 28;20(3):1-8. Co-author.

Newgard CD, Sanchez BJ, Bulger EM, Brasel KJ, Byers A, Buick JE, Sheehan KL, Guyette FX, King RV, Mena-Munoz J, Minei JP, Schmicker RH; ROC Investigators. A Geospatial Analysis of Severe Firearm Injuries Compared to Other Injury Mechanisms: Event Characteristics, Location, Timing, and Outcomes. Acad Emerg Med. 2016 May;23(5):554-65. doi: 10.1111/acem.12930. Epub 2016 Apr 15. Co-author.

Johnson M, Cheskes S, Ross G, Verbeek R. Double Sequential External Defibrillation and Survival from Out-of-Hospital Cardiac Arrest: A Case Report. Prehospital Emergency Care. 2016;20:662-666.Co-author.

Drennan IR, Strum RP, Byers A, Buick JE, Lin S, Cheskes S, Hu S, Morrison LJ. Out-of-Hospital Cardiac Arrests in High Rise Buildings: Delays to Patient Care and Survival. CMAJ. 2016;188:413-419.Co-author.

Kurz MC Prince DK, Christenson J, Carlson J, Stub D, Cheskes S, Lin S, Aziz M, Austin M, Vaillancourt C, Colvin J, Wang HE for the ROC Investigators. Association of Advanced Airway Device with Chest Compression Fraction During Out-of-Hospital Cardiopulmonary Arrest. Resuscitation. 2016 Jan 1;98:35-40. Co-author.

Nichol G; Callaway C; Isaacs M; Vaillancourt C, Sopko G; Idris A; Ornato J; Richardson JD; Cheskes S; Leroux B; Kudenchuk P; Stephens SW; Egan D; Weisfeldt M; Straight R; Condle JP; May S; Schmicker RH ; Morrison LJ; Rea T; Aufderheide T; Stiell I; Christenson J and the ROC Investigators. Trial of Continuous or Interrupted Chest Compressions during CPR. New England Journal of Medicine. 2015 Dec 3;373:2203-2214. Co-author.

Cheskes S, Schmicker RH, Rea T, Powell J, Drennan IR, Kudenchuk P, Vaillancourt C, Conway W, Stiell I, Stub D, Davis D, Alexander N, Christenson J, and the Resuscitation Outcomes Consortium (ROC) investigators. Chest compression fraction: a time dependent variable of survival in shockable out-of-hospital cardiac arrest. Resuscitation. 2015 Dec;97:129-135. Principal Author.

Fernando S, Cheskes S, Howes D. Hands-On Defibrillation and ECG Artifact Filtering Technology Increase Chest Compression Fraction and Decrease Peri-shock Pause Duration in a Simulation Model of Cardiac Arrest. Canadian Journal of Emergency Medicine. 2015 Nov 26. Co-author.

Czarnecki A, Morrison LJ, Qiu F, Cheskes S, Koh M, Wijeysundera HC, MD, Verbeek PR, Austin PC, Dorian P, Scales DC, Tu JV, Ko DT. Association of prior beta-blocker use and the outcomes of patients with out-of-hospital cardiac arrest. American Heart Journal. 2015 Nov 1;170(5):1018-1024. Co-author.

Osei-Ampofo M, Cheskes S, Byers A, Drennan IR, Buick JE, Verbeek PR. A novel approach to improve time to first shock in Prehospital STEMI complicated by Ventricular fibrillation. Prehospital Emergency Care. 2015 Oct 30. Senior Responsible Author.

Morrison L, Hill MD, Tymianski M, Raftis P, Wright G, McAuley G, Verbeek R, Cheskes S, Dundas P, Kakar P, Neville G, Christensen J, Harris D, Leslie PR, Dick W, Swartz R, Selchen D, Casaubon L, Perez Y, Mehdiratta M, Benavente O. The FRONTIER trial: Field randomization of NA-1 treatment by early responders. Int J Stroke 2015; 10 (Suppl. 4); 36. International Journal of Stroke. 2015 Oct;10(Suppl 4):36. Co-author.

Drennan I, Buick J, Cheskes S. Outcomes after Out-of-Hospital Cardiac Arrest by Basic vs. Advanced Life Support. JAMA Internal Medicine. 2015 Aug 4;175(8):1421-1422 (Trainee publication, PHD Student). Senior Responsible Author.

Mausz J, Cheskes S. The impact of prehospital resuscitation research on in-hospital care. CJEM. 2015 Jul 13;17(5):551-557. Invited editorial. Senior Responsible Author.

Nichol G, Stiell I, Leroux B, Cheskes S, Idris A, Kudenchuck P, Machphee, Witmer L, Rea T, Rac V, Gorman K. Post-Discharge outcomes after resuscitation from out-of-hospital cardiac arrest: A ROC PRIMED Substudy. Resuscitation. 2015 May 19;93:74-81. Co-author.

Sutton RM, Case E, Brown SP, Atkins DL, Nadkarni VM, Kaltman J, Callaway C, Idris A, Nichol G, Hutchison J, Drennan IR , Austin M, Daya M, Cheskes S, Nuttall J, Herren H, Christenson J, Andrusiek D, Vaillancourt C, Menegazzi JJ, Rea TD and Berg RA on behalf of the ROC Investigators. A Quantitative Analysis of Out-of-Hospital Pediatric and Adolescent Resuscitation Quality - A Report from the ROC Epistry - Cardiac Arrest. Resuscitation. 2015 Apr 19;93:159-163. Co-author.

Cheskes S, Hillier M, Zahn C, Byers A, Verbeek PR, Morrison LJ. The association between manual mode defibrillation, pre-shock pause duration and appropriate shock delivery when employed by basic life support paramedics during out-of-hospital cardiac arrest. Resuscitation. 2015 Mar 13;90:61-66. Principal Author.

Cheskes S. Resuscitation duty cycle in out-of-hospital cardiac arrest. Resuscitation. 2015 Jan 1;87:A5-6. Principal Author.

Cheskes S, Byers A, Zahn C, Silver AM, Morrison LJ. The impact of compression release velocity on outcomes from out-of-hospital cardiac arrest. Resuscitation. 2015 Jan;86:38-43. Available from: http://dx.doi.org/10.1016/j.resuscitation.2014.10.020. Principal Author.

Vaillancourt C., Charette M., Kasaboski A., Hoad M., Larocque V., Crête D., Logan S., Lamoureux P., McBride J., Cheskes S., Wells G.A., Stiell I.G. Cardiac Arrest Diagnostic Accuracy of 9-1-1 Dispatchers: A prospective multi-centre study. Resuscitation. 2015;90:116-120. Co-author.

Honours and Awards

HONOURS AND CAREER AWARDS
Distinctions and Research Awards
INTERNATIONAL
-The Abigail and Gary Conrad Emergency Medicine Research Award, U Penn (university of Pennsylvania), Philadelphia, Pennsylvania, United States. (Research Award, Specialty: Emergency Medicine)
-“Top 12 papers of 2015 to impact clinical practice”, New England Journal of Medicine. (Research Award)
Trial of Continuous or Interrupted Chest Compressions during CPR.
-Best cardiac arrest presentation winner, NAEMSP. (Distinction)
The impact of peri-shock pause on survival from out-of- hospital shockable cardiac arrest during the Resuscitation Outcomes Consortium PRIMED trial. 
-Best scientific presentation winner, NAEMSP. (Distinction)
The impact of peri-shock pause on survival from out-of- hospital shockable cardiac arrest during the Resuscitation Outcomes Consortium PRIMED trial. 
-“Best poster presentation” winner, NAEMSP. (Distinction)
“Does Prehospital CPAP impact the mortality and morbidity of acute respiratory emergencies”. 2013 

NATIONAL

-“Top 4 in Canadian Emergency medicine Research”, CAEP. (Research Award)
The impact of peri-shock pause on survival from out-of-hospital shockable cardiac arrest during the Resuscitation Outcomes Consortium PRIMED trial. 
Nominated

PROVINCIAL / REGIONAL
Received

-Department of Family and Community Medicine Research Excellence Award (Senior), University of Toronto. (Research Award, Specialty: Emergency Medicine)
-Service Recognition Award for Medical Oversight in EMS (20 years), Ontario Base Hospital Group. (Distinction)
-Lifetime Achievement Award, Ontario Paramedic Association. (Distinction)
Awarded for Excellence in Prehospital Care.

LOCAL

-Hospital Achievement Award, Emergency Medicine Service, William Osler Health System, Brampton Memorial Hospital Campus. (Distinction)
-Dr. Sheldon Cheskes Bursary Award for Excellence in Paramedic Education, RESCU, St. Michael’s Hospital, University of Toronto. (Distinction)
To be awarded to a paramedic on a yearly basis showing excellence in prehospital research and education.
-Quality Award of Excellence, Trillium Health Centre. (Distinction)
ST Elevation Myocardial Infarction: Quality Care Achieved Through Regional Partnerships.
-Hospital Achievement Award, Peel Memorial Hospital. (Distinction)
- Physician Recognition Award Education Committee, Peel Memorial Hospital. (Distinction)

Teaching and Education Awards

LOCAL

-Hospital Achievement Award, Medical Education, William Osler Health Centre, Brampton Memorial Hospital Campus. (Continuing Education)

Grants

2019 July- Principal Investigator. Region of Peel Community Responder Program for out-of-hospital cardiac arrest.Co-investigators and Collaborators. Snobelen Paul, Nevils,Gordon, Drennan, Ian. Zoll Medical Corporation Investigator Initiated Grant. 261,250 CAD(Grants)

2019 May- Principal Investigator. AED on the Fly: A Drone Delivery Feasibility Study. Co-investigators and Collaborators. Snobelen Paul, Nolan, Michael, Collaciti Greg, Reece Philip, Vaillancourt Christian, Dainty Katie, Brooks Steven, Chan Tim. Zoll Medical Corporation Investigator Initiated Grant. 50,000 CAD(Grants)

2019 May Co-investigator. Neighbours Saving Neighbours: Planning a Community Volunteer Resuscitation Program For Victims of Out-of- Hospital Cardiac Arrest in Canada. Principal Investigator: Steve Brooks. Co-investigators: Robert Acheson, Michael Feldman, John Tallon, Peter Thorpe, Farhan Banji, Erin Brennan, Jim Christenson, Gareth Clegg, Katie Dainty, Brian Grunau, Laurie Morrison, Adam Szulewski, Christian Vaillancourt, CIHR Planning Grant 15,000 CAD (Grants)

2019 April-March 2020 Principal Investigator. AED on the Fly: A Drone Delivery Feasibility Study. Co-investigators and Collaborators. Snobelen Paul, Nolan, Michael, Collaciti Greg, Reece Philip, Vaillancourt Christian, Dainty Katie, Brooks Steven, Chan Tim. CANet (Cardiac Arrhythmia Network of Canada). 150,000 CAD(Grants)

2019 Mar- July 2022 Principal Investigator. Double Sequential External Defibrillation in Refractory Ventricular Fibrillation. The DOSE VF randomized controlled trial. Collaborator (s). Verbeek Richard, Mcleod Shelley, Scales Damon, Morrison Laurie, Pinto Ruxandra, Lin Steve, Ko, Dennis, Dorian Paul.Heart and Stroke Foundation- Grant in Aid. 283,347 CAD (Grants)

2018 Nov Co- Investigator. Finalist, Angel’s Den. St. Michaels Hospital Research Competition. AED on the go. Improving public access to automated external defibrillators. Collaborator (s) Dorian, Paul, Anargan Paul, Umapathy K. Brooks S. 25,000 CAD (Grants)

2018 July- 2020 June Co- Investigator. AED on the go. Improving public access to automated external defibrillators. Michael R. Freeman Innovation Competition. Collaborator (s) Dorian, Paul, Anargan Paul, Umapathy K. Brooks S. 150,000 CAD (Grants)

2017 June- 2020 June Co-Principal Investigator. Targeted Initiatives to Decrease the Burden of Sudden Cardiac Death in Canada – A CANet-CanROC Collaboration. Collaborator (s) Lin Steve, Dorian Paul, Christian Vaillancourt, Katie Dainty, Chris Fordyce, Brian Grunau, Laurie Morrison, Jim Christenson. CanNet Grant 1,246,942 CAD (Grants)

2017 May- 2018 May Principal Investigator. Double Sequential External Defibrillation in Refractory Ventricular Fibrillation. The DOSE VF randomized controlled trial. Collaborator (s). Verbeek Richard, Mcleod Shelley, Scales Damon, Morrison Laurie, Pinto Ruxandra, Dorian Paul. Laerdal Foundation Grant 22,500 US dollars (Grants)

2017 May- 2022 May Co-Investigator. The Epinephrine Randomized Optimal Versus Current Dose (EpiROC) Canada Trial. CIHR Project Grant. Collaborator(s): Dorian, Paul; Lin, Steve; Morrison, Laurie J,Brooks, Steven C; Cheskes, Sheldon; Christenson, James M; Dainty, Katie N; Drennan, Ian; Scales, Damon C; Stiell, Ian G; Thorpe, Kevin E; Vaillancourt, Christian; Verbeek, P. 2,509,200 CAD (Grants)

2017 May- 2018 May Co-Investigator. Resuscitation in Motion (RiM) 2018 - From Research to Real World Resuscitation - Dissemination and knowledge exchange for best practice. Collaborator(s): Baker A, Brooks S, Buick J, Chan T, Cheskes S, Christenson J, Dainty K, Dorian P, Drennan I, Grunau B, Gupta S, Jensen J, Lin S, Orkin A, Parsons J, Rizoli S, Rose L, Rotstein O, Scales D, Thoma B, Tijssen J, Vaillancourt C, Vaillancourt S, Verbeek PR, Welsford M, deCaen A. CIHR Grant 15,000 CAD (Grants)

2017 Mar- 2019 Mar Collaborator. Determining Long-Term Outcomes Important to Sudden Cardiac Arrest Survivors & Families. Sunnybrook AFP Innovation Grant. Collaborator(s): Katie Dainty, Richard Verbeek, Damon Scales, Joe Sexton. 95,000 CAD (Grants). Research exploring the long term outcomes of patients sustaining OHCA.

2016 Jul - 2018 Dec Principal Investigator. FIRST Study- Field implementation of the AutoRiC device in ST segment elevation myocardial infarction. HTX. REACH Grant. REACH Grant. Collaborator(s): Richard Verbeek, Paul Dorian, Dennis Ko, Madhu Natarajan, Dominic Raco, Bob Singh, Laurie Morrison. 710,000 CAD. [Grants]
Research exploring the impact of remote ischemic conditioning for patients with STEMI.

2015 Dec - 2016 May Collaborator. The Canadian Cardiac Arrest Witness Registry Think Tank: Working together to build an interactive citizen engagement opportunity. Canadian Institutes of Health Research (CIHR). Planning and Dissemination Grant– Institute Community Suppor. 354855. PI: Dainty, Katie. Collaborator(s): Dr. S. Brooks Mr. J. Buick Dr. S. Cheskes Dr. L. Morrison
Dr. C. Vaillancourt. 24,550 CAD. [Grants]
Think tank on improving rates of bystander CPR.

2015 Jul - 2020 Jul Co- Principal Investigator. CanROC- Canadian Resuscitation Outcomes Consortium:Toward a National Resuscitation Clinical Research Network. Canadian Institutes of Health Research (CIHR). ICRH Community Development Grant. PI: Morrison, Laurie. Collaborator(s): Stiell, Ian, Christenson, Jim, Dorian, Paul, Vaillancourt,Christian. 1,500,000 CAD. [Grants]
Development of a Canadian Resuscitation research network based on the lessons learned from ROC over the last 10 years. Development of a national cardiac arrest registry as well as the opportunity to do interventional and observational research in cardiac arrest, trauma, and pediatric resuscitation.

2015 Jul - 2020 Jul Co- Principal Investigator. CanROC- Canadian Resuscitation Outcomes Consortium:Toward a National Resuscitation Clinical Research Network. Heart and Stroke Foundation of Canada (HSFC). ICRH Community Development Grant. PI: Morrison, Laurie. Collaborator(s): Stiell, Ian, Christenson, Jim, Dorian, Paul, Vaillancourt,Christian. 1,500,000 CAD. [Grants]
Development of a Canadian Resuscitation research network based on the lessons learned from ROC over the last 10 years. Development of a national cardiac arrest registry as well as the opportunity to do interventional and observational research in cardiac arrest, trauma, and pediatric resuscitation.

2015 Jun - 2018 Co-Investigator. A Pragmatic Strategy Empowering Paramedics to Assess Low‐Risk Trauma Patients with the Canadian C‐Spine Rule and Selectively Transport them Without Immobilization. Ontario SPOR SUPPORT Unit. IMPACT Award. PI: Vaillancourt , Christian. 1,456,990 CAD. [Grants]
This trial will look at decreasing the use of C spine immobilization by paramedics in pre-hospital care.

2015 - 2020 Co-Principal Investigator. Paramedic Initiated Treatment of Sepsis Trial in Out-of-hospital Patients (PITSTOP). Canadian Institutes of Health Research (CIHR). Heatlh Services and Policy Research. 342603. PI: Scales Damon. Collaborator(s): Dr. S. Cheskes Mr. I. Drennan Dr. T. Mazzulli Dr. A. Morris Dr. L. Morrison Dr. G. Rubenfeld Dr. C. Seymour Dr. P. Verbeek. 900,555 CAD. [Grants]
A randomized controlled trial investigating the impact of paramedic identification and treatment of sepsis in the prehospital care field.

2014 Nov - 2015 Nov Co-Principal Investigator and Supervising Investigator. Finding the Sickest Patients: Validation of a Prehospital Sepsis Screening Tool. Ontario Paramedic Research Consortium. PI: Cheskes, S. Collaborator(s): Mausz J, Tavares W, Turner L, MacCalman, Alvarez R. 3,865 CAD. [Grants]

2014 Oct - 2017 Sep Co-Investigator. The Frontier Trial - Field Randomization of NA-1 Treatment In Early Responders. NoNO Inc. PI: Morrison, Laurie. Collaborator(s): Morrison L, Benavente O, Casaubon L, Cheskes S, Christenson J, Demchuck A, Dick W, Goyal M, Hill M, Martin R, Mehdirata M, Perez Y, Selchen D, Swartz R, Tymianski M, Verbeek PR. 1,600,000 CAD. [Industrial Grants]

2014 Oct - 2017 Sep Co-Investigator. The Frontier Trial - Field Randomization of NA-1 Treatment In Early Responders. Brain Canada. PI: Morrison, Laurie. Collaborator(s): Morrison L, Benavente O, Casaubon L, Cheskes S, Christenson J, Demchuck A, Dick W, Goyal M, Hill M, Martin R, Mehdirata M, Perez Y, Selchen D, Swartz R, Tymianski M, Verbeek PR. 6,578,920 CAD. [Grants]

2014 Principal Investigator. The association between chest compression release velocity and clinical outcomes from out-of-hospital cardiac arrest. ZOLL Medical Corporation. Collaborator(s): Cheskes S, Common M, Byers A, Zhan C, Morrison L. 15,000 CAD. [Industrial Grants]

2013 Sep - 2016 Sep Co-Investigator. Assessing and improving the quality of care of patients with out-of-hospital cardiac arrest. Canadian Institutes of Health Research (CIHR). Operating Grant. PI: Ko, D. Collaborator(s): Ko D, Austin P, Morrison L, Stukel T, Wijeysundera H, Cheskes S, Rac V, Tu J, Dorian P, Scales D, Verbeek R. 443,022 CAD. [Grants]

2012 Jan - 2013 Jun Principal Investigator. Does prehospital CPAP impact the treatment and mortality of acute respiratory emergencies? Ontario Paramedic Research Consortium. Collaborator(s): Cheskes S, Turner L, Thomson S, Aljerian N, Summers J. 2,500 CAD. [Grants]

2011 Oct - 2015 Oct Co-Principal Investigator. The ICE-PACS randomized control trial. A trial investigating the ability of pre hospital hypothermia and its impact on in hospital cooling rates. Canadian Institutes of Health Research (CIHR). Operating Grant. PI: Scales D. Collaborator(s): Scales D, Morrison LJ, Brooks S, Thorpe K, Mamdani M, Dainty K, Perreira T, Cheskes S, Craig A, Verbeek R, Darling S. 945,275 CAD. [Grants]

2011 Jan - 2012 Dec Co-Investigator. Death notification in the field: A pilot study. Ontario Paramedic Research Consortium. PI: Douglas, Lee ann. Collaborator(s): Douglas L, Ratanpalan S, Cheskes S, Feldman M. 15,000 CAD. [Grants]

2010 - 2016 Co-Principal Investigator. From Bench to Bedside to Curbside. Clinical Research Consortium to improve Resuscitation Outcomes. Heart and Stroke Foundation of Canada (HSFC). PI: Morrison, Laurie. Collaborator(s): Nathens A, Slutsky AS, Dorian P. 1,500,000 CAD. [Grants]

2010 - 2016 Co-Principal Investigator. Resuscitation Outcomes Consortium Core Training Grant. National Institutes of Health & Heart and Stroke Foundation of Canada & Canadian Institute of Health Research. PI: Morrison, Laurie. Collaborator(s): Nathens A, Slutsky AS, Dorian P. 335,000 USD. [Grants]

2010 - 2016 Co-Principal Investigator. From Bench to Bedside to Curbside. Clinical Research Consortium to improfeb ve Resuscitation Outcomes. National Institutes of Health (NIH) (USA). PI: Morrison, Laurie. Collaborator(s): Nathens A, Slutsky AS, Dorian P. 648,000 USD. [Grants]

2009 - 2016 Co-Principal Investigator. From Bench to Bedside to Curbside. Clinical Research Consortium to improve Resuscitation Outcomes. Canadian Institutes of Health Research (CIHR). Institute of Circulatory and Respiratory Health (ICRH). PI: Morrison, Laurie. Collaborator(s): Nathens A, Slutsky AS, Dorian P. 1,057,000 CAD. [Grants]

2002 - 2003 Co-Investigator. The Reliability and Validity of CTAS Assignment in the Prehospital Setting. Ontario Ministry of Health and Long-Term Care. Collaborator(s): Murray M, Vandersluis R, Affleck A, Arcieri V, Welsford M, Schwartz B, Cheskes S. 105,143 CAD. [Grants]